When toothache occurs, patients are advised to go to the stomatology department of the hospital in a timely manner, and under the guidance of the doctor, dental films, curved body laminae and cone beam CT and other related examinations are performed to clarify the cause of the disease, and then the fastest way to stop the pain is to treat the cause. Patients are advised to rinse with warm water or take oral pain medication to temporarily relieve the symptoms of toothache, commonly used drugs include acetaminophen tablets and ibuprofen extended-release tablets. There are more diseases that cause toothache, and targeted treatment can stop the pain faster. For example, for toothache caused by periodontitis, periodontal abscess and other diseases, puncture can be performed to drain the pus, and then oral anti-inflammatory drugs such as metronidazole can be administered for systemic treatment; for toothache caused by pulpitis, periapical infection and other diseases, anesthesia is needed to open the pulp for decompression and drainage to relieve the symptoms of toothache; if the toothache is caused by tooth dislocation, the tooth needs to be preserved and performed within 2 hours of reimplantation. However, it is worth noting that toothache may also be due to non-dental factors such as trigeminal neuralgia, angina pectoris, and acute maxillary sinusitis, which should be identified and given targeted treatment. In addition, patients should develop the habit of maintaining good oral hygiene in their daily life, learn the correct way to brush teeth, pick a suitable toothbrush, ensure sufficient time for brushing, rinse their mouth in time after meals, and use dental floss reasonably to clean the food residues between teeth. Go to dentistry regularly for scaling and cleaning to avoid periodontal diseases.