Hypoadrenocorticism can be categorized into primary and secondary. Primary refers to hypoadrenalism caused by damage to the structure and function of the adrenal glands themselves, while secondary mostly refers to adrenal hypoadrenalism due to hypothalamo-pituitary diseases. Treatment needs to be based on the specific cause of the disease, including medication and surgery. Primary hypoadrenocorticism is mostly caused by immune factors and has a certain heredity. Treatment generally requires long-term corticosteroid replacement supplementation, including glucocorticoids and saline corticosteroids, such as cortisone and desoxycorticosterone. Secondary hypoadrenocorticism is mostly caused by hypothalamus or pituitary gland lesions. If it is caused by pituitary tumors, surgical treatment may be needed, and the levels of adrenal hormones, thyroid hormones and gonadal hormones need to be detected after the operation, and medication substitution therapy, such as cortisone and levothyroxine, etc., will be carried out according to the results of the examination. If there is any discomfort, it is recommended to seek timely medical treatment under the guidance of a doctor.