Joint replacement surgery is one of the effective ways to treat end-stage joint disease in middle-aged and elderly people. It is an effective way for patients to restore motor function and improve their quality of life. Effective analgesia not only reduces pain, anxiety, and sleep, but also allows patients to regain maximum joint function, get out of bed early, and prevent complications such as venous thrombosis. The more commonly used analgesic methods for joint replacement clinically include postoperative analgesic pumps and intraoperative incisional injection of mixed local anesthetic drugs, which include epidural analgesic pumps, peripheral nerve block analgesic pumps and intravenous analgesic pumps. Epidural analgesic pump The epidural analgesic pump is a fine catheter placed by lumbar anesthesia during surgery and connected to an analgesic pump after surgery to give analgesic drugs to achieve analgesia. The analgesic effect is precise. The disadvantages are that the lower limbs cannot be moved during analgesia, a catheter needs to be placed routinely, and there is more nausea and vomiting caused by anesthetic drugs. 2.Peripheral nerve analgesic pump The peripheral nerve analgesic pump is a thin catheter placed around the nerve related to the replaced joint and connected to the analgesic pump to give analgesic drugs. The analgesic effect is more desirable. Since a joint is not innervated by only one nerve, sometimes analgesia may be incomplete or several nerves need to be punctured at the same time, prolonging the operation time; likewise, the analgesic lower limb cannot move well. 3.Intravenous analgesic pump Intravenous analgesic pump is simple to operate and can be done by placing a catheter through a vein, but it uses systemic medication, with more complications such as nausea and vomiting, intestinal distension and affecting consciousness, and the analgesic effect is not as good as the first two. At present, there are two kinds of analgesic pumps in use: pulse type and self-control type, the former gives drugs at a given rate; the latter is the patient’s own control of drug dose according to the self-perception of pain, which can reduce the amount of drugs used. Injecting mixed drugs for analgesia in the incision during surgery Injecting mixed drugs in the incision and around the joint during surgery to achieve postoperative analgesia. The analgesic effect is precise, and the analgesic effect is comparable to the use of analgesic pumps, and the amount of anesthetic drugs used and postoperative bleeding is greatly reduced, and there are almost no side effects such as nausea and vomiting. In our department, the use of mixed drugs injected around the incision in the surgical incision has resulted in almost pain-free or mild pain after joint replacement; no side effects of anesthetic drugs, and significantly higher patient satisfaction; and greatly reduced the amount of postoperative bleeding and blood transfusion, with most patients not requiring blood transfusion. Of course, in addition to incisional local medications, patients can also choose to use analgesic pumps for pain relief.