What is a prostate puncture? Prostate puncture is the abbreviation for prostate puncture biopsy, which is decisive in confirming the diagnosis of prostate cancer and other tumors. Prostate puncture biopsy can obtain prostate tissue and is an important tool to confirm the diagnosis of prostate cancer. When a suspicious hard node in the prostate is found on rectal examination, prostate puncture biopsy can be performed under ultrasound guidance for early diagnosis of prostate cancer. Prostate puncture biopsy is needed when the following indications are found: 1. To determine the nature of prostate mass. 2. 2. To determine the histological type of prostate tumor in order to decide the treatment plan. 3. To determine the effect of prostate cancer after treatment. 4.For patients with elevated serum PSA and PAP, clinical symptoms and rectal examination suspected to be prostate cancer. Timing of prostate puncture: Because bleeding from prostate puncture affects the clinical staging of imaging. Therefore, prostate puncture biopsy should be performed after MRI and other examinations and under the guidance of B-ultrasound. Number of prostate puncture stitches: Systematic puncture biopsy is accepted by most physicians. The results of studies have shown that the diagnostic positivity rate is significantly higher with more than 10 punctures than with less than 10 punctures, with no significant increase in complications. There are two routes for prostate puncture biopsy, one trans-perineal and one trans-rectal, of which the trans-perineal route is not much used in clinical practice, while the trans-rectal route is more accurate in taking material, such as under rectal ultrasound guidance, and its accuracy is higher, although it is more prone to infection than the trans-perineal route, but its application is increasing at present because of its high positive biopsy rate. The development of prostate puncture needles has made prostate puncture biopsy safer, more reliable, and with fewer postoperative complications. The main steps are as follows: 1. The patient is placed in a bladder truncated or lateral position. 2, Routine disinfection and perineal infiltration anesthesia is performed. 3, The needle is inserted 0.5 cm outside the center of the perineum to the midpoint of the anus, and the left index finger is inserted into the rectum or the puncture needle enters the perineum under the guidance of rectal ultrasound. 4.Pierce the puncture needle to the lesion, pull the trigger of the puncture gun, then pull out the puncture needle and push out the needle core to see the prostate tissue.