The TSH is an important pituitary hormone that maintains normal thyroid function in the body. During pregnancy, TSH changes should be observed and any abnormalities found need to be corrected in time and need to be reviewed regularly. In the early stages of pregnancy, TSH varies a lot due to the influence of HCG, and the number of nail function rechecking should be increased. However, high TSH is not an indication for termination of pregnancy, but needs to be combined with fetal 3D ultrasound and other tests. If there is no abnormal fetal development, the pregnancy can continue normally. It is recommended to review the thyroid function weekly and adjust the medication of Eugenol in time. In the middle and late stages of pregnancy, when the condition is relatively stable, thyroid function can be rechecked every month. If a significant increase in TSH is found, prenatal diagnosis, such as amniotic fluid or cord blood puncture, is recommended. If the fetus is found to have severe chromosomal abnormalities, such as trisomy 21, the pregnancy can be terminated, while if the chromosomes are normal there is no indication for termination of pregnancy. Pregnant women are advised to continue their pregnancy under the joint management of an endocrinologist and obstetrician. In addition, if high TSH is found during pregnancy, the child’s thyroid function needs to be reviewed after the birth of the newborn. If abnormalities are found, it is recommended to visit the pediatric endocrinologist for systematic treatment under the guidance of a physician.