Taking antibiotics for genital herpes is not always effective. Genital herpes is not effective on antibiotics if there is no co-infection; if there is a bacterial infection, antibiotics have a therapeutic effect. Genital herpes is a sexually transmitted disease caused by the herpes simplex virus and is treated with antiviral drugs. Whether taking antibiotics is effective or not is mainly categorized into the following two situations; 1. Combined bacterial infection: genital herpes, if combined with infection, usually need oral antibiotic treatment along with antiviral drugs to inhibit and sterilize bacteria. 2. No bacterial infection: genital herpes causes blisters and pain, etc. In the absence of a combined bacterial infection, oral antibiotics have no therapeutic effect, and the lesions will heal on their own after 7 to 10 days without treatment. Genital herpes if the use of antibiotics need to be used under the guidance of a doctor, not self-medication to avoid adverse reactions.