Maintaining the endometrial thickness at 8~14mm is suitable for implantation, when the endometrium is more tolerant to blastocysts and the success rate of blastocyst implantation is high. Endometrial thickness is an important factor for successful implantation, but the tolerance of the endometrium is also very important. The endometrium provides a high-quality intrauterine environment for embryo implantation through functional as well as morphological changes. When the endometrium is larger than 8mm, the endometrium is the most tolerant and the probability of successful blastocyst adsorption, implantation and localization is high. Patients need to be aware of the possibility of endometrial thinning, clinically, when the follicle of the menstrual cycle is greater than 1.8 cm and estradiol is greater than or equal to 200 pg/mL, the thickness of the endometrium is still less than 0.8 cm, which is known as a thin endometrium. In order to ensure successful fertilization of the fertilized egg and to improve endometrial tolerance and blastocyst implantation, medical interventions are required as prescribed by the physician. Currently, estrogen supplementation is used either orally or vaginally to stimulate the endometrium to proliferate for therapeutic purposes. Additionally, supplemental therapies, such as vitamin E and aspirin, can improve endometrial blood flow and thicken the endometrial lining, thus improving the pregnancy rate. It is recommended that patients go to a regular hospital for examination and choose the appropriate treatment plan according to their symptoms.