Vitamin B2 deficiency in patients with hypertension needs to be taken as needed under the supervision of a physician and is not recommended for long-term use. Hypertension must be treated with antihypertensive drugs. The choice of antihypertensive drugs is based on the patient’s physical condition and the cause of high blood pressure. Diuretics, calcium antagonists, beta-blockers, angiotensin inhibitors, etc. can be used. Vitamin B2, also known as riboflavin, has an important physiological role in the human body, involved in the body’s biological oxidation and energy metabolism, can improve the utilization rate of protein in the muscle, maintain the integrity of the skin and cell membranes. It has the function of protecting the mucous membrane of skin follicles and sebaceous glands. Participate in cell growth and metabolism, is the muscle tissue metabolism and repair of essential nutrients. Vitamin B2 is mainly used for the prevention and treatment of vitamin B2 deficiency, such as xerostomia, dry and cracked lips, tongue inflammation, scrotal inflammation and so on. In the state of normal renal function almost no toxicity, after taking the urine is yellow, but does not affect the continued use of the drug. It must be taken in the recommended dosage and not in excess. If too much is ingested, various manifestations such as itching, paralysis, burning sensation and tingling of the skin may occur, and long-term use is not recommended. Hypertensive patients are mainly symptomatic with antihypertensive drugs, which need to be taken under the guidance of a doctor.