High pituitary prolactin in men has a certain relationship with drug factors, pituitary prolactinoma, etc., which can be treated under the guidance of the doctor by using medication, stopping medication or adjusting lifestyle habits. 1. Drug factors: if men take metoclopramide tablets, verapamil and other drugs, can antagonize the prolactin release inhibitory factor, so that the pituitary prolactin is slightly elevated, and after stopping the drug, it can be normalized, and does not require special treatment. 2. Pituitary prolactinoma: patients with this disease will produce prolactin inhibitory factor, so that the level of prolactin increased, can follow the doctor’s instructions to apply bromocriptine mesylate tablets and other drugs, can affect the anterior pituitary hormone prolactin, to achieve the purpose of improvement. It is recommended that patients undergo relevant examinations in the endocrinology department to clarify the cause of the disease and then treat the symptoms, and control the development of the disease as soon as possible.