Melanin production is a complex physiological process, while excessive melanin production or pigmentary disorders (various discolorations, inflammatory hyperpigmentation) is a pathological process or an enhanced physiological response. Therefore, the selection of whitening agent or whitening prescription agent is not simply a cosmetic matter, but must be integrated with the basic facial skin condition, basic skin problems, dermatological clinical characteristics of pigmentation spots and exact diagnosis, and regular and reasonable whitening agent and related clinical treatment should be given under the guidance of professional dermatologists and closely followed up. Nowadays, people’s demand for the treatment of facial skin problems is gradually increasing, both in terms of efficacy, little or no side effects, safety, and comprehensive and integrated improvement of skin problems. Therefore, the treatment of facial skin diseases has gradually transitioned from a single drug treatment to a comprehensive, complete and cosmetic treatment. This requires dermatologists to master all aspects of comprehensive treatment of facial skin diseases and provide patients with a more complete treatment plan, from the initial diagnosis and treatment of the disease to the later recovery of the skin, including daily skin care, to do their best! With the development of dermatology and more attention to facial skin diseases, the in-depth research on whitening agents conducted by the clinical dermatology department (cosmetic department) has made the selection and use of whitening agents safer, more professional and more efficient. Selection of whitening agents (whitening cosmetics) (whitening formulas): Before selecting a suitable whitening agent, you must be interviewed by a professional dermatologist and have a comprehensive assessment of your skin, as described in the Survey and Assessment Form for Facial Skin Problems and Whitening Agent Use, and customize your individual treatment and care plan according to different basic skin conditions and pigmentation. Note: Because of the skin disorders involved, the use of medical cosmetic skin care products is highly recommended and medical skin care will be the future trend in skin care. The sunscreen multiplier of sunscreen is SPF+ PA; there are more types of restorative agents, you can choose EGF and other common restorative agents; the mechanism of action and classification of whitening agents are explained in detail in other articles, you can cross-reference yourself! 1.Neutral skin, and no other skin problems, skin type III, IV, pigmentation is only epidermal pigmentation, light color, light brown, scattered distribution, young patients. →Choose program: sun protection (low or medium times) + whitening (tyrosinase inhibitor). 2.Dry skin, and no other skin problems, skin type III, IV, pigmentation manifestation is only epidermal pigmentation, light color, light brown, scattered, young patients, →Choose program: sunscreen (low or medium times) + moisturizer (hyaluronic acid) + whitening agent (tyrosinase inhibitor), with essence import. ? 3, combination skin and oily skin: except for slightly enlarged pores, no other skin problems, skin typing Ⅲ, Ⅳ, pigmentation performance is only epidermal pigmentation spots, light color, light brown, scattered distribution, young patients, azelaic acid main role of lipid suppression anti-inflammatory anti-keratinization whitening, highly recommended for oily skin patients, moisturizers can be used according to the skin after cleansing, skin reaction as appropriate. → select program: sunscreen (low or medium times) + skin cleansing (oil control and dispel fat) + whitening agent (tyrosinase inhibitor + azelaic acid) + moisturizer (as appropriate) 4, on the basis of the above-mentioned various skin classification, older and wrinkles, and because of longer pigmentation time, in the treatment program, add collagen (with the import) to lighten wrinkles, in addition to the choice of whitening agent and whitening cosmetics, in addition to the necessary The tyrosinase inhibitor, to add any one of the following whitening agents, endothelin antagonist, licorice flavonoids, pigment reducer, because the skin appears aging, apply keratin exfoliator if necessary, in view of the above, such patients must doctor interview, specific customized treatment plan. →Choice program: collagen + whitening agent (tyrosinase inhibitor + any one of other mechanism whitening agent) + keratin exfoliator 5. On the basis of the above various skin classifications, pigmentation is more, color is partly black and longer, pigmentation is in the superficial layer of epidermis or dermis, such patients must be interviewed, skin diseases have been formed, and the next step of treatment can be carried out only after the professional doctor’s diagnosis is clear, part of the tissue level Patients with superficial and relatively light color, after comprehensive evaluation, can undergo photon or laser treatment for fast and effective spot removal, and after surgery, they must strictly protect themselves from sunlight and undergo professional medical cosmetic repair, including fiber repair + moisturizing + whitening (requirements: small side effects, safety and high efficiency); for some patients with pigmentation problems, such as chloasma, after comprehensive evaluation, laser or photon treatment is not possible, such patients can Combined treatment. →Choose program: medical laser or systematic whitening drug + sunscreen (medium times or more) + whitening agent (one or two combined) + post-operative restorative 6. If the above type of skin is sensitive skin, with mild allergy symptoms, not used irritating topical drugs or hormones, with few pigmentation spots and superficial, you can soothe and whiten at the same time. →Choose program: soothing and whitening essence + whitening agent (tyrosinase inhibitor / pigment reducer / endothelin antagonist / licorice extract) + VC 7.If the allergic dermatitis is heavy, and there are pigmentation spots formed by medication and hormones, such patients should be treated first for sensitive skin problems, provided that irritating drugs and suspected allergy-causing cosmetics must be stopped, and try to choose medical skin care products, and choose Before choosing various care products, we must go through a sensitivity test to make sure there is no allergy before use, and do a good job of strict sun protection. →Choose program: compound glycyrrhizin + VC + VE + moisturizer + whitening and allergy relief essence + whitening agent (tyrosinase inhibitor / pigment reducer / endothelin antagonist / licorice extract) + restorative agent (after disease stabilization, can be added)