Sleeping with a stuffy nose is mainly caused by rhinitis, including chronic simple rhinitis, chronic hypertrophic rhinitis, acute rhinitis and allergic rhinitis, etc. It can be relieved by using glucocorticosteroid nasal sprays, saline rinses, antibiotics, and anti-allergy medications according to the cause of the disease and symptoms. 1. Sleeping with a blocked nose is usually caused by chronic rhinitis, especially chronic simple rhinitis, which is characterized by alternating nasal congestion on one side of the nose, which is more pronounced when sleeping and is usually intermittent. Chronic hypertrophic rhinitis is characterized by persistent nasal congestion, either unilateral or bilateral. All of the above cases can be treated with nasal spray glucocorticoids, such as mometasone furoate nasal spray, budesonide nasal spray, etc., you can also use saline to rinse the nose. 2. Acute rhinitis or chronic rhinitis acute attack will also appear nasal congestion, such as confirmed bacterial infection, you can choose amoxicillin and cephalosporin and other drugs for treatment. 3. If it is caused by allergic rhinitis, you can use some anti-allergy drugs, such as loratadine, etc., and you can also use physiological seawater nasal spray and saline rinse nasal cavity. It is recommended that the patient actively consult a doctor for a clear diagnosis, the use of medication under the guidance of the doctor, not unauthorized use of medication.