Bilateral thyroid gland echogenic rough unevenness may be subacute thyroiditis, Hashimoto’s thyroiditis, hypothyroidism and other diseases, need to take treatment for the cause of the disease. 1. Subacute thyroiditis: If the patient’s thyroid ultrasound examination reveals that the thyroid gland has simple uneven echoes, it is mostly considered to be caused by subacute thyroiditis. Patients can use drugs to improve symptoms such as ibuprofen, celecoxib, and glucocorticosteroids such as prednisone acetate under the guidance of doctors. 2. Hashimoto’s thyroiditis: For Hashimoto’s thyroiditis caused by bilateral thyroid gland echogenic rough uneven, if the patient has no clinical symptoms, and the thyroid function is normal, can not be treated. For patients with combined hypothyroidism, it is necessary to follow the doctor’s instructions with levothyroxine sodium tablets and other drugs to supplement thyroid hormones. In addition, if the patient’s thyroid gland is obviously enlarged and exerts pressure on the surrounding organs, or if cancer is suspected, surgical removal of the thyroid gland is needed. 3. Hypothyroidism: Bilateral echogenic roughness and unevenness of thyroid glands caused by hypothyroidism need to be treated with thyroid hormone supplementation drugs, such as levothyroxine sodium tablets, as prescribed by the doctor. Bilateral thyroid gland echo rough uneven may also be hyperthyroidism, thyroid cancer and other diseases. It is recommended that patients with bilateral uneven echogenicity of the thyroid glands need to consult a doctor in time, and the doctor will treat the cause of the disease.