Heartburn and stomach distress are mainly caused by the following reasons: 1. mental stress or frequent late nights, resulting in sleep deprivation. 2. improper diet, when patients have irregular meals, do not eat on time or overeating, will lead to heartburn and stomach distress. 3. may be caused by hypoglycemia and electrolyte disorders, it is recommended to go to the hospital for electrocardiogram examination. 4. heart disease, such as myocardial ischemia, coronary heart disease, myocardial infarction, etc. 5. 5. In addition to the above causes, gastrointestinal diseases are also an important cause of panic and stomach upset, such as acute and chronic gastritis and gastric ulcer. If long-term panic, stomach upset, must go to the hospital to do gastroscopy and other related aspects of the examination, to find the cause of the right medicine.