If a mother-to-be has an intolerable dental condition that must be treated during pregnancy, what is the most appropriate time? Generally speaking, the most appropriate time is between the 4th and 6th month of pregnancy. Receiving treatment in the first trimester can easily induce miscarriage, and in addition, because of early pregnancy reactions, many pregnant women will vomit and become nervous and anxious making treatment impossible. In the last trimester, pregnant women with a large belly can feel extremely uncomfortable in the dental chair, especially if they have a history of preterm labor, so it is best to avoid dental treatment in the last few months, therefore, the best time to see a mother-to-be is in the middle trimester. It is also very important that the mother-to-be should not take any medication for toothache, otherwise it will have adverse effects on her health and that of the fetus, and the adverse consequences for the fetus may be lifelong. Therefore, it is important to consult your doctor first on what and how to take the medicine.