Eating hormone drugs during pregnancy may have adverse consequences on fetal development, so hormone drugs are generally prohibited during pregnancy, if special circumstances require hormone drugs, they need to be used under the guidance of a doctor, and cannot be taken blindly by themselves. Pregnant women in early pregnancy if large doses of cortisone and prednisone and other glucocorticoids, easy to cause fetal harelip, cleft palate, but also lead to middle and late placental insufficiency, so that the newborn weight loss or preterm delivery, or even stillbirth. Application of synthetic estrogen to pregnant women within 3 months of gestation can feminize male fetus and cause abnormalities of reproductive organs in adulthood, such as epididymal cysts, testicular dystrophy, scrotal necrosis, changes in sperm morphology and quantity and reduced survival rate; application of male hormones, such as testosterone, can masculinize female fetus. If the above synthetic hormones are applied after the third month of pregnancy, it can make the female fetus with external genital deformities, such as hypertrophy of clitoris, fusion and adhesion of labia, and so on. In addition, all kinds of hormones are prone to make the fetus intellectually impaired after birth, especially when taken by pregnant women in the early stages of pregnancy, resulting in a greater likelihood of intellectual impairment. Therefore, early pregnancy is more sensitive to drugs, if you need to use estrogen and progesterone to preserve the fetus, you should use natural estrogen and progesterone, such as a small amount of estradiol valerate and natural progesterone under the guidance of a doctor, and strictly grasp the indications. If you become pregnant while taking hormonal drugs, it is recommended that you consult with your gynecologist, who will inform you of the name of the drug, the time of use, and make a comprehensive judgment as to whether it will have a serious effect on the fetus.