Loratadine eaten with a burning sensation in the stomach may be a drug-induced gastrointestinal adverse reactions. Loratadine is an antihistamine that is commonly used clinically to relieve various symptoms caused by allergic reactions, such as sneezing, nasal congestion and itchy nose, hives, etc.; common adverse reactions include fatigue, headache, drowsiness, dry mouth, dermatitis, gastrointestinal discomfort. Because loratadine has a certain stimulating effect on the gastric mucosa, resulting in heartburn after taking. When there is a burning sensation in the stomach after taking loratadine, drink some warm water and observe whether the symptoms are relieved; if the symptoms can be relieved, the next time to take the drug is recommended to be placed in half an hour after the meal, which can appropriately reduce the stimulation of the drug on the gastrointestinal tract; if the symptoms of gastric discomfort are not relieved, the drug should be discontinued and seek medical attention in time to find out the cause of the problem and then carry out the appropriate treatment. Before taking the drug should pay attention to, to loratadine drug components of allergy is prohibited; pregnancy and lactating women, arrhythmia history of patients, renal insufficiency, patients with abnormal liver function need to be used under the guidance of a professional doctor. The medication should be taken according to the doctor’s instructions, do not take medication on your own, and please consult a doctor in time if you feel unwell.