The hardened acne on the face can be treated by general treatment, medication and physical therapy. 1. General treatment: usually avoid high sugar, high fat and spicy diet, reduce protein intake, use warm water to wash your face, eat fresh vegetables and fruits, do not scratch the skin to avoid infection. 2. Medication (1) Topical medication: such as benzoyl peroxide gel can sterilize, anti-inflammatory, dissolve the keratinous plugs, which can reduce the symptoms. If accompanied by infection, topical clindamycin can be used to inhibit the growth of Acinetobacter acnes and anti-infection treatment. (2) Oral medication: If external medication is ineffective or fails to improve, oral medication can be used, such as antibacterial drugs doxycycline and erythromycin, etc. Oral retinoic acid and isotretinoin can also be used to inhibit sebum secretion, but they are teratogenic and are prohibited to be used by women who are preparing for pregnancy or during pregnancy. 3. Physical therapy: commonly used treatment modalities include photodynamic therapy, chemical exfoliation therapy, laser therapy, etc., which are generally applicable to patients who are ineffective in drug therapy or cannot tolerate drug therapy. Patients who have grown up with hardened acne on their face are advised to go to the hospital in time and under the guidance of the doctor to carry out active treatment. Do not use medication without authorization to avoid adverse reactions.