Positive Hepatitis B IV and V indicates that one has been infected with the Hepatitis B virus, but it does not indicate that one is a Hepatitis B patient, and it needs to be judged in conjunction with the results of the Hepatitis B Surface Antigen and Hepatitis B Surface Antibody tests. Hepatitis B IV and V positivity refers to the positive e antibody and core antibody in Hepatitis B V, which are produced by the autoimmune system, and the reason for the production is exposure to its corresponding antigen. It indicates that one has been infected with the hepatitis B virus, but it does not indicate that one is a hepatitis B patient. It is often necessary to determine this based on the results of the hepatitis B surface antigen and hepatitis B surface antibody tests, and of course, sometimes it is necessary to perform hepatitis B virus DNA quantification to further determine this. If the hepatitis B surface antigen is positive at the same time as the hepatitis B IV or V positive, it means that the patient is suffering from hepatitis B. However, if the hepatitis B surface antibody is positive at the same time, it means that the hepatitis B virus has already been cleared from the body and only traces of the viral infection are left behind for the production of the antibody. However, if only hepatitis B 4 or 5 positive and hepatitis B surface antigen and surface antibody are negative, then further quantification of hepatitis B virus DNA is needed to determine whether hepatitis B virus exists in the body. Therefore, whether hepatitis B 4 or 5 positives can be recognized as hepatitis B patients depends on the results of hepatitis B surface antigen and surface antibody, and further hepatitis B virus DNA quantitative examination is needed if necessary.