Many patients wonder if there is a possibility of epilepsy after brain surgery. Seizures after brain surgery are related to the site of surgical injury, and observation of the clinical seizure characteristics of postoperative epilepsy can help locate and identify the epileptogenic lesion. The incidence of epilepsy due to brain injury is higher in the motor areas of the cerebral cortex and in the parietal lobe near the central sulcus. Temporal lobe injuries, especially hippocampal and amygdala injuries, also occur frequently and have a short latency period. Therefore, there is also a strong relationship between different surgical sites and post-brain surgery epilepsy. Seizures do not occur immediately after brain surgery. The average latency period for seizures after open cranial trauma is six months, and the average latency period for seizures after closed injury is October. Frontal lobe injuries tend to manifest as generalized seizures, parietal lobe injuries tend to occur as focal motor seizures, and temporal lobe tend to be psychomotor seizures. In left-sided brain injury patients, the impairment of consciousness appears earlier and manifests as tonic-clonic seizures, right-sided limb convulsions, urinary incontinence, head-eye deflection, disorientation, aphasia, obsessive-compulsive symptoms, thought-sensory impairment, and even continuous seizures. Those with predominantly right-sided brain injury tend to present with loss of consciousness, left-sided limb and facial convulsions, head-eye deflection, mental disorder, hallucinations, sudden collapse, or generalized tonic seizures. How to treat secondary epilepsy after brain surgery? Surgical treatment is effective, using electrical stimulation to stimulate a wide range of areas caused by the original seizure aura with limited localization value. On this basis they summarized this technique and proposed for the first time a new method of localization using electrical stimulation to induce seizures, i.e., combining intracranial electrode recording and stimulation data for localization of epileptic foci, and surgical excision of both the electrically stimulated seizure area and the recording area. For the sake of their own safety and health, patients should go to a regular professional hospital for treatment as soon as epilepsy occurs.