Secondary diabetes may be caused by the use of certain medications, or it may be caused by disease factors such as acute pancreatitis or pheochromocytoma. It may be cured if it is caused by medication, or if it is caused by disease, it can be cured after removing the cause, but it is difficult to be cured if the pancreatic β-cells have failed. 1. Drug factors: long-term use of methylprednisolone, prednisone and other glucocorticosteroids may be elevated blood glucose, such cases caused by elevated blood glucose can generally be restored after stopping the drug. 2. Disease factors: patients with acute pancreatitis may experience elevated blood glucose, which can be restored after standardized treatment, but repeated episodes of pancreatitis may lead to the destruction of pancreatic islet β-cells, and secondary diabetes mellitus is difficult to be cured in such cases. Patients with pheochromocytoma may have abnormal glucose metabolism leading to elevated blood glucose, which can return to normal after pheochromocytoma is cured. Patients diagnosed with secondary diabetes should cooperate with their doctors.