Atrophic gastritis with bullous erosion needs to be treated with medication, surgery, and general measures to regulate. 1. Drug treatment: atrophic gastritis with rumbling erosion can be used under the guidance of the doctor Ranitidine, cimetidine and other H2 receptor antagonists, as well as aluminum thiosulfate, magnesium bicarbonate and other gastric mucous membrane protective agents. Some patients also need to use mosapride, domperidone and other drugs to promote gastrointestinal motility. For atrophic gastritis caused by Helicobacter pylori infection, it is necessary to follow the doctor’s instructions to take the quadruple therapy, that is, two antibiotics + bismuth + proton pump inhibitors, commonly used drugs include metronidazole, amoxicillin, bismuth potassium citrate, omeprazole and so on. 2. Surgical treatment: If atrophic gastritis with bulging erosion appears mild heterotrophic hyperplasia, regular follow-up observation is needed. For patients with severe heterotrophic hyperplasia, endoscopic surgery or open surgery is needed. 3. General measures: patients need to develop regular eating habits, can not long-term smoking and drinking, can not eat moldy, pickled food, you can eat vitamin and protein-rich foods, such as tomatoes, cucumbers, apples, milk, lean meat and so on. In addition, patients need to maintain a relaxed mood and avoid anger. It is recommended that patients with atrophic gastritis with rumbling need to seek timely medical treatment, the doctor will choose the appropriate measures for treatment according to the patient’s condition, and the drugs should be used in accordance with the doctor’s instructions.