Polycystic ovary syndrome is an endocrine disorder syndrome in which reproductive dysfunction coexists with abnormal glucose metabolism. Persistent anovulation, multiple follicular immaturity, androgen excess and insulin resistance are its important features and are the most common causes of menstrual disorders and infertility in fertile women. The etiology and pathogenesis of polycystic ovary syndrome are very complex, with infertility mainly caused by anovulation or sporadic ovulation. First of all, endocrine examination is needed to exclude androgen increase and insulin resistance, treatment should be adjusted lifestyle, weight loss, male semen examination and tubal examination, if they are normal, ovulation promotion therapy can be used after weight control and androgen reduction. Patients with polycystic ovary syndrome have hyperinsulinemia and are prone to diabetes mellitus and cardiovascular diseases, and therefore are also at high risk for diabetes mellitus and cardiovascular diseases. If there is no requirement for fertility, regular progesterone supplementation is needed to withdraw blood, protect the endometrium and prevent cancer. This patient does not need to be presumptuous and overly worried, receive regular examination and guidance, and will be happy for life!