Zhi Bai Di Huang Wan (知柏地黄丸) and Da Tian Yin Wan (大补阴丸) both have the effect of nourishing yin and lowering fire (nourishing yin essence and lowering fire), and together they are used to treat a series of diseases caused by yin deficiency of the liver and kidneys (insufficient yin in liver and kidneys) resulting in excessive fire. Zhi Bai Di Huang Wan (知柏地黄丸) is composed of Zhi Mu (知母), Huang Bai (黄柏), Radix Rehmanniae Praeparata (熟地黄) and Mudan Pi (牡丹皮), etc. It has the efficacy of nourishing yin and lowering fire, and is used as the main treatment for yin and kidney yin deficiency resulting in lumbar and knee soreness and tenderness (a feeling of weakness and weakness of waist and knees), five heartburns and heat (feverishness of the hearts of the hands and the feet and self-consciousness of the heart and chest irritation and stuffiness and heatiness), hot flushes (a bout of heatiness), night sweating (abnormal perspiration after falling asleep but the sweating stops upon waking up), and seminal emission. Dazhongyin Pill is composed of Radix Rehmanniae Praeparata, Rhizoma Zizoma Polygonati Odorati, Cyperus Rotundus, etc. It has the effect of nourishing yin and lowering fire, and is mainly used for treating the symptoms of five heartburns and heatiness caused by deficiency of yin of liver and kidney and inflammation caused by deficiency fire. Note: Avoid indigestible food; not suitable for patients with cold and fever. Zhi Bai Di Huang Wan and Da Tonic Yin Wan are used together to treat symptoms of five heartburns and heat, coughing and hemoptysis, night sweating, zygomatic redness (redness of cheeks and zygomatic bones) caused by deficiency of liver and kidney yin and inflammation caused by deficiency fire. The adverse reactions and contraindications of the two drugs have not been clarified. In addition, please note that Zhi Bai Di Huang Wan should be taken with caution; pregnant women should take it with caution; it is not suitable for patients with deficiency-cold syndrome, which is characterized by fear of cold, cold hands and feet, and preference for hot drinks. If you feel unwell and need to take medication, please go to the hospital and take medication under doctor’s guidance.