Severe vomiting belongs to severe vomiting of pregnancy, and the treatment includes medication to stop vomiting, replenishment of water and electrolytes, and termination of pregnancy if necessary. 1. Drugs to stop vomiting: The first-line drug is vitamin B6, which can be taken or applied intravenously to relieve the symptoms of vomiting, and metoclopramide, ondansetron and other drugs can be used to stop vomiting. 2. Supplementation of water and electrolytes: patients with severe vomiting in pregnancy should be hospitalized in time to clarify the situation of water loss and electrolyte disorders, and supplement water and electrolytes as appropriate, as well as give intramuscular injection of vitamin B1. 3. Termination of pregnancy if necessary: After treatment, the patient’s condition improves and the pregnancy can be continued. In case of life-threatening conditions such as persistent liver function abnormality and persistent elevation of body temperature, termination of pregnancy should be considered. If the pregnant woman is found to have severe vomiting, she should go to the hospital in time and follow the doctor’s instructions for treatment.