Ranitidine is rarely used at present mainly because of its slow onset of action, acid suppression time is short, adverse reactions and other disadvantages, in the clinic has been replaced by proton pump inhibitors.
Ranitidine belongs to the Hâ‚‚ receptor antagonist, mainly through the inhibition of basic gastric acid and stimulating factors caused by gastric acid secretion, so that gastric acid secretion is significantly reduced, clinically can be used for peptic ulcer, reflux esophagitis, gastrinoma and other diseases treatment. However, the efficacy of ranitidine on peptic ulcer is slow, acid suppression time is short, easily affected by diet, and more adverse effects, can cause arrhythmia symptoms, neuropsychiatric symptoms, gastrointestinal symptoms, allergies and other side effects.
With the emergence of new acid-suppressing drugs, the acid-suppressing effect of proton pump inhibitors represented by omeprazole is more powerful, and it has gradually replaced ranitidine as the first-line acid-suppressing drug for the treatment of gastrointestinal diseases. The specific use of medication should follow the doctor’s instructions.