Interventional treatment for uterine disease

  Patients with uterine fibroids and adenomyosis often come to the clinic to consult about related matters. I find that the questions raised by patients are often similar, so I will give a focused answer to the most concerned questions.  1.Does it hurt a lot after the intervention for fibroids and adenomyosis?  A: Interventional treatment for fibroids and adenomyosis is performed by embolizing part of the uterine artery or uterine fibroid artery to necrosis the diseased tissue for therapeutic purpose. The causes of post-interventional pain are mainly due to the following: (1) the uterine artery is not super-selectively cannulated, resulting in excessive embolization of the uterine artery or ectopic embolization; (2) the size and type of embolization material: the size of the embolization material determines the size of the embolized vessels, and different embolization materials lead to different reactions of the organism and produce different pain sensations; (3) the patient’s sensitivity to pain is different. Among these three factors, the first 2 factors are controllable and can be avoided or reduced by careful manipulation and embolic agent selection for postoperative pain. In more than two-thirds of the patients done in our department, the pain is not severe and the duration of pain is usually several hours-3 days. Basically, all patients can return to normal in 5-7 days. Therefore, patients can not worry too much about postoperative pain.  2.Will ectopic embolism be produced during the interventional treatment of fibroids and adenomyosis?  A: As long as the formal imaging examination and careful selection of embolization materials are carried out, basically no embolization will occur. The principle of ectopic embolism is mainly due to arteriovenous fistula or vascular variation, which causes embolic agent to enter the circulation through these abnormal vessels. These conditions can be detected in formal angiography and therefore these complications can be largely avoided. We have not found any patients with ectopic embolism in hundreds of cases.  3. Does the recovery after intervention produce ovarian failure?  A: It is possible, but the chances are small. The normal ovary is mainly supplied by the ovarian artery, which originates from the renal artery or the lateral wall of the abdominal aorta and is not on the same trunk as the uterine artery, but in some patients, the uterine artery sends out an ovarian branch to supply the ovary. The principle of ovarian impairment is the embolization of the ovarian branch of the uterine artery, which is the main blood supplying artery to the ovaries, during treatment. Generally speaking, even if the ovarian artery is embolized during uterine artery embolization, it does not cause ovarian damage because often the ovarian branch of the uterine artery is not the main blood supply artery to the ovaries. In addition, if the ovarian artery is found in the pre-embolization angiogram, the ovarian artery will usually be super-selected for embolization to avoid the ovarian artery.  4.Can I have children again after the intervention?  A: Yes, but it is not advocated. There are many reports on fertility after interventional treatment at home and abroad, which show that the fertility function is not significantly affected after interventional treatment. However, the following factors after interventional treatment may affect fertility: first, patients need to be exposed to X-ray radiation during interventional treatment, although the dose is not large, the effect on ovarian function and eggs has not been studied and there may be potential damage; second, the endometrium of patients after embolization treatment will be damaged to a certain extent, which may affect the fertilization of eggs and lead to miscarriage. Both of these points may have an impact on fertility. Therefore, a cautious attitude is taken regarding fertility after interventional treatment. If you have to have children, you should have children after 1 year after the operation.  5.What is the recurrence rate of fibroids and uterine adenosis after interventional treatment?  The recurrence rate after interventional treatment of fibroids is low, generally the long-term recurrence rate after surgery is less than 10%, which is lower than that of myomectomy. Uterine fibroids shrink to a certain extent after surgery and then stop shrinking, and then stabilize at a certain size, usually the shrinking process lasts about 1 year. Of course, some smaller fibroids can disappear after intervention.  The 1-year effective rate of adenomyosis is >90% or so, but some patients will recur as time goes on. The literature reports a long term efficiency of about 60-70%.