The full name of the quadrivalent is the 4-valent HPV vaccine. 6 categories of people for whom the 4-valent HPV vaccine is not recommended lack scientific evidence and are false. The 4-valent vaccine has the following vaccination requirements. 1. Age: The 4-valent vaccine is indicated for women aged 9 to 45 years. It is not recommended for women over 46 years of age. After the age of 46, the protection obtained from the vaccination will be reduced accordingly, so it is not recommended. 2. Allergy: People who are allergic to the active ingredient of the vaccine or any of the excipient components should not be vaccinated. If you are allergic to the vaccine, you may have a severe hypersensitivity reaction after vaccination, so it is not recommended. 3. Pregnancy and breastfeeding: It is not recommended for women during pregnancy and breastfeeding. No studies have been conducted to evaluate the effects of this product on women during pregnancy. Valid data (including pregnancy registry information, epidemiologic studies, and unintended pregnancies during clinical trials) collected in pregnant women are not yet sufficient to determine whether vaccination results in a risk of adverse pregnancies, including spontaneous abortions. If a woman is pregnant or intends to become pregnant, it is recommended that the vaccination be delayed or interrupted and that the vaccination be repeated after the end of the pregnancy. 4. Coagulation disorders: It is not recommended for patients with severe coagulation disorders. Vaccination is known to cause bleeding, which may occur in patients with severe coagulation disorders.