Enzyme tissue examination refers to enzyme histochemical staining, special staining and enzyme histochemical staining are methods of pathology examination. Special staining allows for the examination of tissues in cells by staining them; if there are tumor cells, they will be stained blue, while normal cells will not be stained. Special stains are used to show or identify normal structures in the cells, or to identify abnormal substances, lesions, pathogens, etc. that appear during pathology. Enzyme histochemical staining is to detect enzyme activity by using intracellular enzymes that have the property of catalyzing certain reactions. It is commonly used in the diagnosis of blood diseases such as leukemia in clinic, and there are peroxidase staining, neutrophil alkaline phosphatase staining, acid phosphatase staining, etc. Different stains represent different significance, for example, peroxidase staining, if it is positive, is commonly found in acute myeloid leukemia. If special staining or enzyme histochemical staining is found to be positive in the examination, it is recommended to consult a doctor in time to clarify the cause of the disease and then carry out targeted treatment.