Vitamin B2 cannot be used to treat acne, which is medically known as acne. Vitamin B2 is a vitamin drug that can be used for the prevention and treatment of vitamin B2 deficiency, and can improve the effects of keratitis, chapped lips, scrotal inflammation, inflammation of the tongue, conjunctivitis, seborrheic dermatitis, and other diseases. Acne is a chronic inflammatory disease of the sebaceous glands of the hair follicles, mainly caused by Propionibacterium acnes infection, but also related to sebaceous gland keratinization abnormalities, immunity and other factors. Acne treatment, mainly according to the pathogenesis of acne, can be taken to inhibit sebaceous gland secretion, control the propagation of Propionibacterium acnes, regulate hormones in the body, reduce the inflammatory response based on the choice of topical retinoic acid creams as well as antibiotic ointment, such as retinoic acid cream, clindamycin gel, fusidic acid cream, etc., to improve the patient’s symptoms. The use of the above drugs must be applied under the guidance of a professional physician, and must not be used blindly to produce adverse effects on the organism.