New Crown Nucleic Acid Test bottles contain a protective fluid that protects proteins and viral genes to facilitate the testing of nucleic acids, and are available in both inactivated and non-inactivated types.
The inactivated type contains virus lysate in the preservation solution, which can rapidly inactivate the virus after sampling of staff throat swabs, and can reduce the risk of secondary infection. This protective solution also enables the release of viral nucleic acids, which facilitates the detection of the virus. It also maintains the stability of the viral genes and allows for increased efficiency of nucleic acid extraction.
Non-inactivated viruses have no lysate within them and contain solution components that are favorable for culturing viral host cells. This protective solution maintains viral integrity and allows for increased survival time and stability of the virus, but this method requires more protection and preservation temperatures after virus sampling.