Sudden cough and chest tightness can be caused by many reasons, clinically seen in pneumothorax, bronchial foreign body, cardiac disease. 1. Pneumothorax: Before the onset of the disease, a small number of patients may have to hold heavy objects, breath holding, strenuous physical labor and other triggers, there are also patients in normal activities or quiet rest occurs. Most of the patients have a sudden onset of chest pain on one side, which lasts for a short period of time, followed by chest tightness and dyspnea, which may be accompanied by irritating cough. When pneumothorax occurs, activities should be minimized and medical attention should be sought immediately. 2. Bronchial foreign body: foreign body into the trachea can cause coughing, at the same time there can be chest tightness, dyspnea and other manifestations. You should go to the hospital immediately to remove the foreign body to minimize complications. 3. Heart disease: in acute heart failure, there will be sudden severe dyspnea, chest tightness, frequent coughing, coughing pink foamy sputum. It should be noted that sudden coughing and chest tightness can be caused by a variety of causes, should go to the local hospital to improve the examination, clear diagnosis, and treatment by professional doctors.