There is no quick relief for hot hands after cutting peppers. General treatment should be given first, and if the symptoms are obvious, relief can also be provided by medication. 1. General treatment: use flowing water or soapy water to wash in time, remove the residual capsaicin and other substances on the hands. Reduce the irritation, you can also use ice, cool towels and other cold compresses to reduce edema and relieve pain. As capsaicin or capsaicinoids can be dissolved in alcohol or vinegar, you can also use white wine or vinegar to smear the affected area several times, and then rinse with water, which can effectively reduce the symptoms. 2. Medication: If there is no relief through general treatment, or even if the symptoms continue to worsen, you can use topical medication, such as glycerine lotion, hydrocortisone ointment, fluoride acetate easy cream and other drugs. Specific medication should be under the guidance of a doctor.