Generally speaking, how long it takes to take Anrotinib for the tumor to shrink is related to the development of the disease and so on, and cannot be generalized. Anrotinib belongs to anti-vascular drugs, which can inhibit the proliferation of many kinds of tumor cell lines, and is clinically used in the third-line treatment of non-small cell lung cancer, and also used in the treatment of bowel cancer, thyroid cancer and other diseases. Combined with the specific conditions of patients, the drug can be used for combination chemotherapy or combination immunotherapy. The exact onset of action varies from person to person, and there is no definite onset of action. Anrotinib is usually taken orally for two weeks in a course of treatment, followed by a one-week break. However, it is not possible to accurately assess how long it will take for tumors to shrink or for amlotinib to work. A common adverse reaction to Anrotinib is rash, and in some patients it may cause increased blood pressure and mouth ulcers. Therefore, during the use of Anrotinib, it is necessary to observe while treating, combined with the patient’s own condition under the guidance of the doctor to standardize the use of medication.