The cause of subcortical ischemic foci in the frontal lobe is usually related to atherosclerosis of the blood vessels supplying the anterior cerebral circulation. The blood vessels supplying the anterior cerebral circulation are mainly the anterior cerebral artery and its branches. When atherosclerosis occurs in the anterior cerebral artery or its branches, chronic ischemia occurs in the frontal lobe supplied by the anterior cerebral artery and its branches, and ischemic foci can be detected by MRI or CT, and the corresponding clinical symptoms such as headache, headache, memory loss, and so forth, or in mild cases, they may be asymptomatic. The development of atherosclerosis is usually associated with many risk factors, such as smoking, high blood pressure, high blood lipids and so on. Risk factors should be controlled to avoid the development and progression of atherosclerosis, thus preventing further progression of ischemic foci. Prompt medical consultation is recommended when subcortical ischemic foci are detected in the frontal lobe.