ABC This is a male patient, 53 years old. He has a 5-year history of diabetes mellitus. He had an open trauma to the left ankle joint due to a car accident in September 2013 and was treated with a flap transfer of the left anterior tibial defect in a local hospital immediately after surgery. Postoperative recovery was possible. Three months after the operation, recurrent rupture and pus flow from the trauma occurred, which was not relieved by dressing change and antibiotics. The sinus tract remained after debridement in the local hospital. After admission, X-rays, CT, MRI, bacterial culture, routine blood biochemistry and other tests were performed. The routine blood tests showed hemoglobin 87g/L, albumin 29g/L, CRP 19, ESR 27. Blood glucose 12.3mmol/L. Bacterial culture showed Staphylococcus aureus infection. X-ray: as shown in Figure A, where the arrows point, the periosteum was rough, and the local defect of bone cortex was a low-density shadow, and the growth of local new bone was a high-density shadow. CT: As shown in Figure B, where the arrow points to, necrotic bone is present, new bone is generated, and the bone marrow cavity is occluded. MRI: As shown in Figure C, where the arrow points, the black low signal shadow is the necrotic tissue in the marrow cavity, and the extent of necrotic tissue can be seen. The typical history of chronic osteomyelitis is open trauma or fracture + recurrent sinus tracts after surgical treatment. Eighty percent of the patients in our department currently have a similar condition. If a patient presents with a similar condition, please quickly find a specialized facility for the treatment of osteomyelitis (Nanjing General Hospital, Nanjing Military Region, Orthopedic Infection Unit, etc.). Delaying the best chance of treatment will potentially face more than 2 surgical procedures.