The symptoms of blood in the stool after staying up late are mainly due to prolonged overwork and lack of sleep, the body’s immune system function and metabolism is prone to abnormalities, which can lead to various diseases, such as rectal inflammation, hemorrhoids, etc. Rectal inflammation is mainly caused by foreign body damage, infection, abnormal immune function and other reasons, clinical manifestations are bleeding stools and the formation of mucus blood stool, and often accompanied by anorectal pain, abdominal pain, diarrhea, constipation and other symptoms, and even cause fever, vomiting and other systemic discomfort symptoms. Patients with internal hemorrhoids mainly present with blood in the stool, which develops into prolapsed internal hemorrhoid nuclei and is accompanied by anal swelling. Patients with thrombosed external hemorrhoids, on the other hand, experience intense pain in addition to blood in the stool. The symptoms of blood in the stool suggest going to a hospital for relevant tests and targeted treatment under the guidance of a doctor.