Midodrine hydrochloride tablets of the drug components can be metabolized to glycine midodrine, agonist alpha adrenergic receptor, usually in half an hour to two hours or so to start the effect, the symptoms of low blood pressure will be relieved. Midodrine hydrochloride is a precursor substance, in the body after 30min~2h transformation can be generated glycine midodrine and reach a large blood concentration, play the role of excitation of adrenergic α-receptors, can be used to improve postural hypotension, stress urinary incontinence and other diseases. The drug has a rapid onset of action, usually immediately upon increase in drug concentration, i.e., half an hour to two hours after taking the drug. Therefore, the drug can be taken in the morning before standing up to prevent postural hypotension. However, it should be noted that the drug is used in combination with severe organic heart disease, acute kidney injury, pheochromocytoma, hyperthyroidism, hypertension and other conditions. Caution is required during pregnancy and lactation, and it is recommended to stop breastfeeding when using the drug during lactation. The drug needs to be used under the guidance of a clinician; adverse reactions such as hypertension, itching, chills, urinary retention, urinary frequency, etc. occur after use of the drug, it is recommended to stop using the drug and seek medical attention.