Armpit odor, also known as localized oedema. It is named after the special odor emitted by foxes, commonly known as “fox odor”. Its incidence is 4.56-6.41%. The main harm is to make others feel uncomfortable, the person himself or herself to produce psychological pressure, which has a negative impact on the patient’s social activities, daily behavior, mental health. The disease is often characterized by a runny stare (i.e., “oily ears”) during adolescence and does not develop until adolescence when the sweat glands are well developed. The histological basis of axillary odor was found to be the hyperplasia of axillary sweat glands through the study of axillary histology. The human sweat glands are divided into large sweat glands and small sweat glands. Small sweat glands are distributed throughout the body and secrete colorless fluid. Macrohidrosis is mainly found in the axillae, areola, umbilicus, perineum and feet, which are hairy or have many folds. The axillary sweat glands are large ductal glands, divided into secretory and ductal parts, with the ducts opening in the hair follicles and a few opening in the epidermis. The distribution range is roughly the same as the range of axillary hair, and is consistent with the number, density and distribution of hair follicles, although there are still a small number of sweat glands at 0.5cm outside the edge of the axillary hair, but there are no sweat glands at 1.0cm. The central axillary crease was the most dense, and gradually became sparse toward the upper and lower ends of the axillary hairs. Most of the axillary sweat glands are located in the superficial subcutaneous fat layer, the deep dermis layer, and a few in the middle dermis layer. From the histopathological and ultrastructural observations, the axillary sweat glands of patients with axillary odor are characterized by a large number of glandular tissues, a large volume of secretory cells, and vigorous development, and are parietal secretory glands. These substances are sterile and odorless, and soon after discharge, they are decomposed by bacteria (Staphylococcus epidermidis, Gram-negative bacteria, etc.) in the moist part of the axilla to produce a substance with volatile odor, mainly unsaturated branched-chain fatty acids of six to ten carbons, mainly 3-trans-2-methylhexanoic acid and 5α-androstenone. Axillary odor is an autosomal dominant disorder with a significant genetic predisposition. The development of acromegaly is influenced by sex hormones, so it develops during puberty, more in females than males, and is most pronounced when exercise and heat lead to overproduction of sweat glands. Because the sweat glands are located in the deeper layers of the skin and fat layer, it is difficult to achieve the root effect of external drugs and superficial treatment, using ionization, laser, sclerotherapy and microwave treatment of axillary odor, most of them can not completely destroy the sweat glands and make the efficacy of the treatment is poor or the disease repeated. Therefore, the sweat glands must be completely destroyed or removed in order to achieve a better treatment effect. Surgery is mainly through the complete destruction, destruction and removal of the local sweat glands and ducts in the axilla, so it has become a more reliable and effective method to eradicate axillary odor.