Novel coronaviruses may affect male fertility, but it is not clear. The novel coronavirus has a very strong affinity for angiotensin-converting enzyme, and can affect many organs in the human body, resulting in abnormalities, and can also invade the human reproductive system, with varying degrees of reduction in the number of spermatogonial cells in the testes, and degeneration of Sertoli and Leydig cells, which may affect male reproductive function. However, since the new coronavirus is a new type of virus, there are fewer cases caused by it, and there is no large amount of data to support the study of complications and sequelae caused by it, so many of the results of the study need to be further analyzed statistically, and the role of the new coronavirus on male fertility cannot be clarified for the time being. As for the new coronavirus pneumonia, the most important thing now is to take preventive measures, do not go to crowded places, wear masks when going out, keep the distance between people, and use running water to clean your hands for more than 15 seconds. Regarding the prevention of new coronavirus pneumonia, it is recommended to consult the public health department of regular hospitals. Tip: In this article, the terms “new coronavirus pneumonia” and “new coronavirus pneumonia” were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.