Idiopathic thrombocytopenic purpura, also known as primary or immune thrombocytopenic purpura, is a relatively common bleeding disorder, the onset of which is mostly seen in women of childbearing age, and can mostly resolve on its own in pediatric patients. The preferred treatment for this disease is glucocorticoid or gammaglobulin therapy: 1, commonly used glucocorticoid: prednisone, also can choose prednisolone, hydrocortisone; after the hormone effective gradually reduce the amount and low dose maintenance, 3-6 months after the discontinuation of the drug, maintenance medication for no more than 1 year. Patients whose platelet count does not reach the standard after 1 month of treatment indicate that the hormone is ineffective; 2, short course of dexamethasone treatment method: 4 days in total, within 6 months the platelet count drops again seriously can be used again; 3, high-dose gammaglobulin: gammaglobulin can inhibit antibody binding with platelets, the effect is faster, high dose for 5 days as a course of treatment, 1 week after the platelet can reach the highest level, the efficiency is high, but the effect is short. The platelet count will return to the original level within 1 month. For patients with ineffective hormone therapy, hormone-dependent patients who are effective but relapse after stopping the drug, or patients with contraindications to hormone therapy, splenectomy or second-line drugs such as danazol and mortezumab are feasible; in case of failure of first- and second-line therapy, stem cell transplantation or alemtuzumab can be chosen.