There is no relationship between the new crown vaccine and swollen feet. Swollen feet may be physiologic or pathologic, such as various kinds of nephritis, kidney disease, heart failure, and foot lesions. 1. Vaccination with inactivated New Crown vaccine may cause some common general reactions, such as soreness, redness, swelling, pain, itching, and low-grade fever at the site of vaccination, etc., which usually do not lead to swelling of the feet and have nothing to do with the injection of New Crown vaccine. 2. Causes of swollen feet. (1) Physiological: Sitting for a long time or walking for a long time will slow down the blood return to the feet and easily cause edema. Usually after resting or elevating the feet, the edema will disappear. (2) Pathological causes of edema include heart failure, various nephritis and kidney diseases, decompensated cirrhosis, malnutrition, premenstrual tension syndrome, use of adrenocorticotropic hormone, and foot infections. After the new crown vaccine appeared foot swelling, exclude physiological factors need to go to the hospital to clarify the diagnosis, and then do the treatment.