The reasons for high blood pressure in the afternoon include irregular drug taking, irrational drug selection, and having secondary hypertension. There are two peaks of blood pressure in human body, 8:00 to 10:00 in the morning and 4:00 to 6:00 in the afternoon, but the peak of blood pressure from 4:00 to 6:00 in the afternoon is lower than that in the morning. In order to control the two peaks of blood pressure, it is recommended to take antihypertensive drugs at 6:00 to 7:00 in the morning, and choose long-acting antihypertensive drugs, which can lower blood pressure smoothly for 24 hours. Poor blood pressure control can also combine two antihypertensive drugs, take one in the morning, and one in the afternoon before 4:00 to 6:00 pm to reduce the afternoon blood pressure peak. Afternoon blood pressure can occur if medication is irregular, not taken at the right time, taken every other day, etc. Poor choice of medication can also lead to high afternoon blood pressure. Choosing short-acting drugs, which need to be taken twice a day, can lead to high blood pressure in the afternoon if you simply take the morning antihypertensive drugs and do not take the antihypertensive drugs in the afternoon. Secondary hypertension, such as primary aldosteronism, pheochromocytoma, renal artery stenosis, renal insufficiency, etc., tends to lead to poor blood pressure control, and some will have high blood pressure in the afternoon. Improve the hypertension five, adrenal CT, renal artery ultrasound examination to confirm the diagnosis. If you have high blood pressure, you should insist on taking antihypertensive drugs and develop good living habits. If the blood pressure control is not up to standard, it is recommended to go to the hospital in time and adjust the antihypertensive drugs according to the doctor’s instructions.