Amniocentesis is a method of prenatal diagnosis and is generally suitable for prenatal diagnosis of mid-term pregnancies. The following matters should be noted before and after having amniocentesis First, do not have intercourse 4-5 days before the procedure, and not within a week after the procedure. Second, if you have a cold or other discomfort before the procedure, be sure to explain to the clinician in advance so that the doctor can reasonably schedule the procedure. If necessary, use contraction inhibiting drugs to suppress contractions before puncture. If you have any drug allergies, you should inform your doctor. If there is any family history of hereditary disease, it must also be explained before the procedure. Sixth, ensure at least two hours of rest after the puncture. It is best not to take a shower or bath for 2 days after the surgery to avoid infection due to water exposure. Eight, scientific diet, pay attention to rest, avoid overexertion, avoid long-distance travel and avoid strenuous exercise within two weeks.