Vulvar leukoplakia rarely progresses to the inside of the vagina, and most appear right on the vulva. Vulvar leukoplakia is hypopigmentation of the skin of the vulva, which manifests itself as limited or diffuse white patches of skin on the vulva. Vulvar leukoplakia is mainly associated with localized skin malnutrition and is most often found in the vulva, rarely progressing to the vagina. The pathogenesis of vulvar leukoplakia is still unclear, can take topical hormonal drugs local application treatment, such as testosterone propionate ointment, progesterone ointment, glucocorticoid cream, etc., the specific medication program should be carried out under the guidance of the doctor. In normal life should pay attention to change underwear, keep the vulva local clean and dry, avoid unclean high-risk sex.