The saturation and concentration of uric acid in the body at 37°C is about 420μmol/L (7mg/dl), above this concentration is hyperuricemia, and long-term hyperuricemia may lead to gout. Clinically, it is divided into primary hyperuricemia and secondary hyperuricemia, and its treatment methods are generally as follows: primary hyperuricemia and gout treatment methods to lower uric acid include: 1. general treatment: control the total calorie of diet; limit the consumption of alcohol and high purine food; drink a lot of water to increase the excretion of uric acid; use drugs that inhibit uric acid excretion such as thiazide diuretics with caution; avoid triggering factors Avoid triggering factors and actively treat related diseases. 2.Treatment of hyperuricemia: The aim is to maintain uric acid at normal level. Mainly include: uric acid excreting drugs such as benzbromarone, drugs to inhibit uric acid production such as allopurinol, alkaline drugs such as sodium bicarbonate, new uric acid lowering drugs such as selective uric acid reabsorption inhibitors. 3. Treatment of acute gouty arthritis: Colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are the first-line drugs for the treatment of acute gouty arthritis and should be used early, but their timeliness and toxic side effects should also be mastered. Management of interictal and chronic phases of gout attacks: Patients with frequent attacks of acute gouty arthritis, chronic gouty arthritis or gout stones should be actively treated with uric acid-lowering therapy. Principles of treatment for secondary hyperuricemia: actively treat the primary disease, avoid or minimize the use of drugs and methods that may trigger and/or aggravate hyperuricemia; control acute gouty arthritis attacks as soon as possible. In addition, hyperuricemia and gout are often accompanied by metabolic syndrome, and comprehensive treatment of blood pressure reduction, lipid reduction, weight reduction and improvement of insulin resistance should be actively carried out. In conclusion, regarding the method of lowering uric acid, we should choose the individualized treatment method suitable for patients according to their etiology and condition, so that we can get half the result with twice the effort.