Hepatitis B is not easily treated with antiviral drugs because antiviral drugs (e.g., entecavir, etc.) may harm the liver, produce adverse reactions, and the virus is resistant to the drugs. 1. Harming the liver: drugs are generally metabolized by the liver and kidneys, and if the dosage is not appropriate, it will increase the metabolic burden on the liver, which will easily induce or aggravate liver disease, so patients with hepatitis B minor triple yang should not blindly use antiviral drugs for treatment. 2. Adverse reactions: Hepatitis B triple III patients with antiviral drugs can produce adverse drug reactions, such as itchy rash, headache, dizziness, fever, loss of appetite, nausea and vomiting and other adverse reactions. 3. drug resistance: if the condition of hepatitis B is relatively mild, liver function indicators are particularly normal is not the need for antiviral treatment, blind use of antiviral drugs can produce drug resistance, so patients with hepatitis B virus infection should not be easily treated with antiviral drugs. Hepatitis B patients who use antiviral drugs to produce physical discomfort should be timely consultation, patients should not self-medication, in the physician’s interview under the guidance of standardized treatment.