There are hard lumps under the skin that do not hurt or itch, considering that they are caused by sebaceous cysts, lipomas, enlarged lymph nodes, etc. It is recommended that medication and surgical treatment be chosen according to the specific cause of the disease. 1. Sebaceous cysts: cysts formed due to the blockage of sebaceous gland ducts and siltation, usually without obvious clinical manifestations. The swelling is usually spherical, smooth surface, without secondary infection, usually no pain, no itching. Surgical excision is often used for treatment. 2. Lipoma: Lipoma is a kind of soft tissue benign tumor, usually without obvious symptoms, often forming painless and itchy local lumps. If the diameter of the lipoma is small and distributed in an isolated manner, it is generally not necessary to deal with it. If the lipoma is large, surgical resection is feasible. 3. Enlarged lymph nodes: when local inflammation occurs in the skin, it can be manifested as enlarged lymph nodes and hard lumps which are painless and itchy. At this time, it is necessary to take oral antibiotics to reduce the inflammation, so that the lymph nodes will be reduced, and the commonly used drugs are cephradine, amoxicillin and so on. If there are hard bumps on the skin that do not hurt or itch, please do not judge on your own and use medication, it is recommended to go to the hospital to find out the specific cause of the disease, and under the guidance of the doctor for symptomatic treatment. The medication should be used according to the doctor’s prescription.