Children with fever and hot hands but cold feet usually continue to have fever. Fever in children with hot hands and cold feet is a phenomenon of fake cold and real heat, especially in infants and children under three years old, mainly because the blood volume in children’s extremities is less than that in the internal organs, due to insufficient blood supply to the extremities, and therefore more likely to get cold than adults. Children’s nervous system is not yet well developed, and the autonomic nerves, which are responsible for managing vasodilation and contraction, are prone to disorders, resulting in spasmodic contraction of small blood vessels at the end of the extremities at the beginning of fever and chills. In addition, because children’s central nervous system is not yet mature, the ability to regulate body temperature is not perfect, and because the body’s immunity is low when the fever is high, the fever usually continues. Parents should pay close attention to the temperature change of the child and take physical cooling methods to reduce the fever in a timely manner, and if necessary, take the child to the pediatric department for fever reduction treatment.