Candida vaginitis is generally referred to as vulvovaginal pseudomycosis, and drug resistance can be treated with a fungal culture, along with a drug sensitivity test, so that a sensitive drug can be selected for treatment. In vulvovaginal pseudohyphomycosis, a fungal culture of the secretions should be performed, and a drug sensitivity test should be performed at the same time as the culture, so that a sensitive drug can be selected for treatment. Drug-resistant Pseudomycosis vulvovaginitis may be complicated, and should be treated with intensive treatment and consolidation therapy. Intensive treatment is to extend the course of treatment by 1~2 courses on the basis of simple vaginitis treatment, and consolidation therapy can be used with fluconazole for 6 consecutive months, and a course of topical medication can be given every month according to the pattern of recurrence, for 6 consecutive months. Vulvovaginal pseudomycosis drug-resistant should do further examination, and actively cooperate with the treatment, the above medication should be used under the guidance of a doctor, avoid self-medication, so as not to cause adverse consequences.