1.AFP Mainly related tumors: hepatocellular carcinoma and germ cell carcinoma. Other related tumors: embryonal cell carcinoma, ovarian teratoma, gastric cancer, biliary tract cancer, pancreatic cancer, etc. Other influencing factors: benign diseases including hepatitis, cirrhosis, enteritis and hereditary tyrosinemia may increase; it may also increase temporarily during pregnancy. 2.CEA is mainly related to tumors: a broad-spectrum tumor marker. Other related tumors: common in lung cancer, colorectal cancer, pancreatic cancer, gastric cancer, breast cancer, medullary thyroid cancer, etc. Other influencing factors: Smokers have more false positives, and serum CEA is also elevated in about 15%~53% of women in pregnancy and patients with cardiovascular disease, diabetes, non-specific colitis and other diseases. 3.CA242 Mainly related tumors: pancreatic cancer, stomach and colon cancer. Other related tumors: liver cancer, esophageal cancer, lung cancer. Other influencing factors: benign gastrointestinal diseases such as pancreatic cancer, hepatitis and cirrhosis of the liver will be elevated in patients. 4.CA125 starring related tumors: ovarian cancer. Other related tumors: lung cancer, pancreatic cancer, breast cancer, liver cancer, gastrointestinal malignant tumors, uterine cancer. Other influencing factors: female pelvic inflammatory disease, endometriosis, menstruation, ovarian cysts, uterine fibroids, chronic hepatitis, pancreatitis, cholecystitis, pneumonia, etc. will be elevated. 5.CA199 Mainly related tumors: pancreatic cancer, bile duct cancer, colorectal cancer. Other related tumors: liver cancer, gallbladder cancer, bile duct cancer, etc. Other influencing factors: It is also elevated in many patients with benign diseases of the digestive system. It is reported that nearly 10% of patients with pancreatitis have moderately elevated serum CA19-9. 6.CA153 Mainly related tumors: the preferred marker for breast cancer. Other related tumors: lung cancer, ovarian cancer, lung adenocarcinoma, colorectal cancer, etc. can be increased. Other influencing factors: serum CA15-3 of patients with benign breast disorders, endometriosis, ovarian cysts, etc. may also exceed the normal value. 7.CA724 Mainly related tumor: one of the best tumor markers for gastric cancer. Other related tumors: It also has different detection rates for other gastrointestinal cancers, breast cancer, lung cancer, ovarian cancer, etc. Other influencing factors: benign diseases have less effect on CA72-4. 8.CA50 Mainly related tumors: Marker for pancreatic and colon and rectal cancers. Other related tumors: gastric cancer, gallbladder cancer, liver cancer, lung cancer, breast cancer. Other influencing factors: CA50 is also elevated at the onset of atrophic gastritis, pancreatitis, colitis and pneumonia. 9.NSE Mainly related tumors: small cell lung cancer. Other related tumors: adenocarcinoma of the lung, large cell lung cancer, and cancer of the nervous system. Other influencing factors: If hemolysis occurs or if there is prolonged stagnation time after blood collection in separating plasma serum or improper centrifugation to destroy cells, it can lead to elevated NSE. 10.CYFRA21-1 Mainly related tumors: squamous lung cancer, cervical cancer, esophageal cancer. Other related tumors: bladder cancer, nasopharyngeal carcinoma, ovarian cancer, gastrointestinal tract cancer. Other influencing factors: hepatitis, pancreatitis, pneumonia, prostate enlargement may also be elevated. 11.f-PSA Mainly related tumors: prostate cancer. Other related tumors: certain gynecological tumors and breast cancer. Other influencing factors: prostate enlargement can cause elevation. 12.t-PSA Mainly related tumor: prostate cancer. Other related tumors: certain gynecological tumors, polycystic ovary syndrome, breast cancer. Other influencing factors: prostatitis and prostate enlargement may cause elevation. 13.Free β-hCG is mainly associated with gynecological tumors and non-seminogenic testicular cancer. Other related tumors: breast cancer, spermatogenic testicular cancer, lung cancer, liver cancer, etc. Other influencing factors: Free β-hCG level may increase when suffering from endometriosis, ovarian cysts and other non-tumor states, pneumonia and prostate enlargement. 14.SCCA Main related tumor: cervical squamous carcinoma. Other related tumors: squamous lung cancer, head and neck squamous cancer, esophageal cancer and vulvar squamous cell carcinoma, etc. Other influencing factors: SCCA values are increased in patients with hepatitis, cirrhosis, pneumonia and tuberculosis. 15.β2-MG Mainly related tumors: Adjuvant markers of malignant tumors, especially in chronic lymphocytic leukemia, lymphocytic sarcoma, multiple myeloma, etc. Other related tumors: elevated in lung cancer, breast cancer, gastrointestinal tract cancer and cervical cancer. Other influencing factors: It can be increased in renal failure, various hematologic diseases and inflammation, and it can be increased in various diseases, so we should exclude the increase of serum β2-MG due to some inflammatory diseases or glomerular filtration function bottoming out.